Impact of Air Pollution on the Autonomic Nervous System Activity and the Presence of Sleep Apnea in Older Subjects (POLLAIR)

Centre Hospitalier Universitaire de Saint Etienne

Status: Completed

Conditions: Healthy

Treatments: Other: Air pollution study on healthy volunteers.

Study type: Observational

Funder types: Other

Identifiers

NCT01042834

0508078

DGS 2006/0060 (Other Identifier)

Details and patient eligibility

About

Impact of air pollution on the autonomic nervous system activity and presence of sleep apnea in older subjects.

Full description

The relation between the air pollution and morbidity, cardiovascular mortality was increasing interest. Analyses show an increase of respiratory difficulty, but also cardiac deaths in the daytime when the atmospheric pollution was increased. It was demonstrated that health effects of ambient air pollution in subjects presenting cardiac or lung difficulty were important. Mechanisms show a possible relation to autonomic nervous system (ANS) deactivation and mortality. Particularly, the ageing and ANS reach would be more predictive of cardiovascular events. Thus, we suggest estimating in 60 healthy volunteers from 60 to 80 years old, the impact of the air pollution on the autonomic nervous system activity and sleep apnea consequences.

Enrollment: 60 patients

Sex: All

Ages: 60 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• reside in Lyon and Saint-Etienne cities
• security social affiliated or beneficiary
• information note signed

Exclusion criteria

• heart rate disorders
• pacemaker
• tabacco addiction or second-hand smoke
• morbid obesity (BMI > 30)
• insulin-dependent diabetes
• chronic disease on treatment
• antiarrythmic treatments

Trial design

60 participants in 1 patient group

Air pollution

Description:

The subjects will have to live in districts where important atmospheric pollution is established

Treatment:

Other: Air pollution study on healthy volunteers.