Impact of an Intensive Multimodal Educative Program on Behavioral Disorders of Patients With Profound Multiple Disabilities and on the Quality of Life and Feelings of Caregivers (TDCHandi)

Assistance Publique - Hôpitaux de Paris

Status: Completed

Conditions: Polyhandicap; Behavior Disorders

Treatments: Behavioral: Intensive educative management

Study type: Interventional

Funder types: Other

Identifiers

NCT02510846

K140701

PHRIP140325 (Other Identifier)

Details and patient eligibility

About

Profound multiple disabilities also called in French polyhandicap are defined by the combination of a deep mental disability and severe motor deficit with extreme restriction of autonomy. Life in institution for people with profound multiple disabilities induces emotional and educative deficiency and often conducts to behavioral disorders. These behavioral disorders also impact on quality of life and feelings of caregivers. An intensive multimodal educative program proposed to patients with profound multiple disabilities can improve their psychic well-being, reduce chronic pain and improve also quality of life and feelings of caregivers. The intensive multimodal educative program will be compared to the usual practice of educative program.

Full description

People with profound multiples disabilities needs particular follow-up with education, care, communication and socialization.

Our hypothesis is that an intensive multimodal educative program of 5 hours a week during 12 months compared to the usual practice of 1 hour a week conducts to the reduction of behavioral disorders and improves the quality of life and feelings of caregivers.

This study is multicenter, controlled, randomized in two parallel groups and open-labelled comparing usual practice of educative program and intensive educative program during 12 months.

The evolution of predominant behavioral disorder and quality of life and feelings of caregivers is evaluated at inclusion (M0), six months after (M6) and twelve months after (M12).

Enrollment: 63 patients

Sex: All

Ages: 3 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Hospitalized patient

• Age between 3 and 35 years old

• Patient with multiple disabilities defined by the following 5 criteria:

  1. reached or causal brain injury occurred before 3 years and
  2. profound mental disability (IQ lower than 35 or not assessable by psychometric tests when patients are too deficient) and
  3. motor disability (para-quadraparesis, hemiparesis, diplegia, ataxia, extrapyramidal motor disorders, neuromuscular disorders) and
  4. reduced mobility ( Gross Motor Function Classification System score: GMFCS III à V) and
  5. extreme autonomy restriction (FMI Functional Independency lower than 50)

• Patient with at least once per week of the following behavioral disorders:

  • Restlessness episodes (refusal of physical or verbal contact expressed by gestures aiming to push off other patients or caregivers and/or shouts when caregivers try to approach).

or

• Unexplained crying: according to the Riccilo S.C, Watterson T [Riccilo 1984] definition: fully or partially closed eyes, facial grim/wince and vocalization with or without tears.

or

• Rumination or
• Bruxism or
• Self-mutilations or
• Heteroagressif behavior (bite, pinch, hit) or
• Gestural stereotypies or
• Rythmic movements or
• Iterative frictions

Exclusion criteria

• No agreement of participation to the study by the holders of parental authority / legal guardian.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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63 participants in 2 patient groups

Intensive educative program

Experimental group

Description:

5 hours a week

Treatment:

Behavioral: Intensive educative management

Usual practice of educative program

Active Comparator group

Description:

1 hour a week

Treatment:

Behavioral: Intensive educative management