Impact of Anti-inflammatory and Antibiotic Therapy on the Emergence of Peri-tonsillar Abscess (APA)

Nantes University Hospital (NUH)

Status: Terminated

Conditions: Abscess, Peritonsillar

Study type: Observational

Funder types: Other

Identifiers

NCT00954031

BRD 08/9-W

Details and patient eligibility

About

Analyze in children and adults, risk factors in the onset of the APA. The main hypothesis focuses on the use of anti-inflammatory in the context of pharyngitis or sore throat before the symptoms of ABS. Secondary objectives:

1. • Analyze the implementation of a rapid diagnostic test and its result on the occurrence of an ABS
2. • Measure the frequency of prescription and describe the reasons for not prescribing an antibiotic for patients who consulted for a sore throat and having developed a PLA
3. • Describe the microbial flora could puncture of patients hospitalized for APA

Enrollment: 711 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• clinical existence of a PLA (phlegmon), validated by a senior ENT, usually (but not necessarily) following a request by an emergency. The visible appearance to the merits throat must justify puncture. Cases will be included whether or not they had consulted for a "sore throat" in the 10 days preceding the date of diagnosis

Exclusion criteria

• Neoplastic disease of the throat, scalable Hematologic with tonsillar localization History of tonsillectomy

Trial design

711 participants in 2 patient groups

case

Description:

hospitalized patients, adult or child, including the diagnosis of APA was made, after consulting their physician.

The control group

Description:

Two patients witnesses will be matched to each case: Chronological criterion: consultation for a "sore throat" 10 days (± 3 days) before the date of hospitalization of cases, between 13 and J-J-7. Age criteria: year of birth ± 5 years Geographical criteria: living in the same department, failing in an adjacent Department Social criteria: beneficiary or otherwise of the CMU, to avoid a selection bias leading social most frequently at the onset of the APA