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Impact of Anxiety and Depression on Implicit and Explicit Memory Performance (ADEM)

I

Islamic Azad University, Tehran

Status

Completed

Conditions

Memory Bias
Implicit Memory
Generalized Anxiety Disorder (GAD)
Explicit Memory
Major Depressive Disorder (MDD)

Study type

Observational

Funder types

Other

Identifiers

NCT06663423
SDU-MEMORY-2024

Details and patient eligibility

About

This study examines the effect of anxiety and depression on memory processes, focusing on implicit and explicit memory. Implicit memory involves unconscious recall, such as recognizing familiar words without effort, while explicit memory requires conscious recollection of specific information. The study aims to investigate whether individuals with depression and anxiety show differences in these types of memory, which may contribute to biases related to their emotional states.

Participants were divided into three groups: individuals with depressive disorder, individuals with generalized anxiety disorder, and a control group with no emotional disorders. Each group was assessed using tasks designed to measure both implicit and explicit memory performance. The goal is to enhance understanding of memory biases in individuals with depression and anxiety, potentially supporting more targeted interventions.

Full description

This cohort study is designed to explore potential memory biases in individuals with depressive and anxiety disorders compared to a control group. The study includes 27 participants divided into three groups: nine individuals diagnosed with major depressive disorder, nine with generalized anxiety disorder, and nine control subjects with no history of emotional disorders. All participants were matched by age and education level.

Participants completed standardized tasks and assessments, including the Spielberger State-Trait Anxiety Inventory and various memory tasks such as word decoding and recognition memory tasks. These tasks aim to evaluate mood-congruent biases in memory recall. Data collection will focus on analyzing any distinct memory processing patterns in depression and anxiety to improve psychological treatment approaches.

Enrollment

27 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Adults aged 18 years or older
  • Individuals diagnosed with major depressive disorder (Group 1)
  • Individuals diagnosed with generalized anxiety disorder (Group 2)
  • Healthy individuals with no history of emotional disorders (Group 3)

Exclusion criteria

  • History of neurological disorders
  • Visual impairments
  • Substance abuse or drug addiction
  • Psychiatric hospitalizations unrelated to primary diagnosis (for Groups 1 and 2)

Trial design

27 participants in 3 patient groups

Group 1
Description:
Depressive Disorder group - 9 participants.
Group 2
Description:
Generalized Anxiety Disorder group - 9 participants.
Group 3
Description:
Control group - 9 participants.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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