Impact of Augmenting Exercise Intensity vs. Frequency

Brendon Gurd, PhD

Status: Unknown

Conditions: Exercise Training

Treatments: Behavioral: Intensity comparison; Behavioral: Frequency comparison

Study type: Interventional

Funder types: Other

Identifiers

NCT04295590

UCD Study

Details and patient eligibility

About

The purpose of this study is to compare the impact of augmenting exercise intensity and augmenting exercise frequency on peak work rate. Participants will complete exercise tests and provide 8 skeletal muscle samples following a within-subjects randomized crossover design utilizing single-leg cycling. Both training periods will be 4 weeks long and skeletal muscle biopsies will be collected from both legs before and after each training period. All exercise sessions will be supervised, take place in the investigator's laboratory, and occur on stationary bikes.

Enrollment: 16 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Recreational active (<3 hours per week of aerobic exercise)
• Willing to provide skeletal muscle biopsies

Exclusion criteria

• Cardiovascular or metabolic disease
• Athletes or individuals exceeding 3 hours per week of aerobic exercise
• Smokers

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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16 participants in 2 patient groups

Frequency then Intensity

Experimental group

Description:

Training period 1: Frequency comparison Training period 2: Intensity comparison

Treatment:

Behavioral: Intensity comparison

Behavioral: Frequency comparison

Intensity then Frequency

Experimental group

Description:

Training period 1: Intensity comparison Training period 2: Frequency comparison

Treatment:

Behavioral: Intensity comparison

Behavioral: Frequency comparison