Impact of Bilateral Deep Parasternal Intercostal Plane Block on Intraoperative Opioid Consumption in Open Heart Surgery

University of Indonesia (UI)

Status: Unknown

Conditions: Opioid Use

Treatments: Procedure: deep parasternal intercostal plane block; Procedure: control

Study type: Interventional

Funder types: Other

Identifiers

NCT05103787

IndonesiaUAnes119

Details and patient eligibility

About

This study aims to assess the impact of bilateral deep parasternal intercostal plane block on intraoperative opioid consumption in open heart surgery

Full description

High-dose opioid is associated with various side effects such as nausea, vomiting, urinary retention, and respiratory depression. The neuraxial block (intrathecal, epidural) and peripheral nerve block are regional anesthesia techniques which have the potential to reduce intraoperative opioid consumption. The deep parasternal intercostal plane block is fascial plane block which intended to block anterior cutaneous branch of intercostal nerves.

This study is a double-blind randomized controlled trial. Thirty subjects will be recruited with consecutive sampling method. Eligible subjects with signed informed consent will be randomized into two groups. The first group is the treatment group who will receive bilateral deep parasternal intercostal plane block after induction of anesthesia and the second group will be the control group who will not receive any regional anesthesia. After surgery, extubation time, adverse event (nausea, vomiting), and intensive care unit length of stay will be recorded for both groups.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 18-70 years old
• Elective open-heart surgery with median sternotomy approach

Exclusion criteria

• Patient who refuses to participate
• Patient with local infection in the block area
• Patient with chronic pain
• Patient with history of chronic analgesics use
• Patient who is contraindicated for local anesthetics
• Patient with cognitive disorder
• Patient with severe psychiatric disorders

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups, including a placebo group

deep parasternal plane block

Active Comparator group

Description:

Subjects will receive bilateral deep parasternal intercostal plane block after induction of anesthesia.

Treatment:

Procedure: control

Procedure: deep parasternal intercostal plane block

control

Placebo Comparator group

Description:

subjects will receive skin puncture with needle on the same location as the treatment group without administration of local anesthetics after induction of anesthesia,

Treatment:

Procedure: control

Procedure: deep parasternal intercostal plane block