Impact of Body Mass Index on Serum Maternal and Fetal Magnesium Level

Assiut University

Status: Unknown

Conditions: Pre-Eclampsia

Treatments: Drug: Magnesium Sulfate

Study type: Observational

Funder types: Other

Identifiers

NCT03928691

MAGPET

Details and patient eligibility

About

Magnesium sulphate is an inorganic salt with multiple therapeutic applications in medicine it has been widely utilized and studied on a diverse set of conditions such as asthma, cardiac arrhythmia and stroke. In pregnant women ,MgSo4 has been used in many cases such as for seizures prophylaxis in preeclampsia, tocolysis in preterm labour and for fetal neuroprotection in immenint preterm delivery.MgSo4 has been used as the standard drug for tocolysis in preterm labour and other drugs have been compared to it.

Enrollment: 400 estimated patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

pregnant women 34 weeks or less admitted to Women's Health Hospital with a diagnosis of :

• sever preeclampsia. It is defined as 1- blood pressure 160/110 mmHg or more 2- proteinurea (+3 or more by dipstick) 3-HELLP syndrome
• threatened preterm labour that will receive Magnesium Sulphate either for tocolysis or neuroprotection.

Exclusion criteria

• women with more than 34 weeks gestation and with any contraindication for Magnesium Sulphate intake like severe renal impairment or myasthenia gravis.

Trial design

400 participants in 1 patient group

Study group

Description:

pregnant women admitted to Women's Health Hospital , Assiut university during 2019-2020 will be counseled to participate in the study

Treatment:

Drug: Magnesium Sulfate