Impact of Chemotherapy on Ovarian Reserve in Young Women With Breast Cancer (Resova)

Nantes University Hospital (NUH)

Status: Terminated

Conditions: Ovarian Reserve

Study type: Observational

Funder types: Other

Identifiers

NCT01114464

BRD/09/06-J

Details and patient eligibility

About

The aim of this protocol is to study the deleterious impact of adjuvant chemotherapy or neoadjuvant chemotherapy on ovarian reserve in young women suffering from breast cancer. A new relevant ovarian reserve marker, serum Anti-Mullerian Hormone, will be used in order to evaluate precisely the impact of chemotherapy on ovaries during chemotherapy administrations and after during follow-up (24 months). This strategy offers 2 main advantages : no modification of the traditional care of patients (treatment, organisation, follow up ...) and use of a non invasive marker (serum). The final objective is to give precise information to patients on their future fertility after remission.

Enrollment: 250 patients

Sex: Female

Ages: 18 to 39 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• female 18-39 years
• suffering from breast cancer
• treated with adjuvant or neoadjuvant chemotherapy

Trial design

250 participants in 1 patient group

young women with breast cancer