Impact of CMV Status on HIV Viral Load Decay

Civil Hospices of Lyon

Status: Completed

Conditions: Hiv

Treatments: Drug: HIV antiretroviral therapy

Study type: Observational

Funder types: Other

Identifiers

NCT03349359

CRC_GHN_2017_006

Details and patient eligibility

About

Background: Cytomegalovirus (CMV) infection is usually observed among patients with HIV infection. No study to date has investigated the impact of CMV infection on HIV viral load decay during antiretroviral therapy.

Methods: 345 consecutive HIV patients coinfected (N=300) or not (N=45) with CMV were enrolled. Clinical, biological and virological data were collected from HIV antiretroviral therapy initiation to the day of HIV viral load undetectability if any.

Enrollment: 345 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• HIV patients starting an antiretroviral therapy
• CMV serology available at antiretroviral therapy initiation
• HIV viral load assessed at each follow-up visit after treatment initiation

Exclusion criteria

• HIV antiretroviral treatment initiation before June 2005