Impact of Corona Vaccination on AMH- Anti Mullerian Hormone (Israel)

Wolfson Medical Center (WMC)

Status: Unknown

Conditions: Patient Participation

Treatments: Biological: Vcinated

Study type: Observational

Funder types: Other

Identifiers

NCT05034679

0013-21-WOMC

Details and patient eligibility

About

Since December 2020 Nationwide anti-COVID-19 vaccination began in Israel using the Pfizer - BioNtech vaccine (BNT162b2 mRNA). The vaccination campaign has been associated with concerns regarding potential detrimental effects on future fertility. The aim of the study is to determine the impact of COVID-19 vaccination on n AMH- Anti Mullerian Hormone which express ovarin function.

disease and/or immunization on human follicular function, by comparing follicular steroidogenesis, response to the LH/hCG trigger, and oocyte quality biomarker (HSPG2), in the aspirated follicular fluid of patients undergoing ovum pick-up.

Full description

Our assumption is that there is no effect of the vaccination on the AMH level. We plan to recruit 90 patients who are divided to three groups First group patients who vaccinated and measure the AMH before and up to 9 months after vaccination. Second group patients who were infected by Covid-19 ant therefor were not vaccinated to compare the AMH level before and after the infectious. The third group patients who were not infected and not vaccinated.

Enrollment: 90 estimated patients

Sex: Female

Ages: 18 to 44 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 18-44

Exclusion criteria

Age over 45

Trial design

90 participants in 3 patient groups

Vaciinated

Description:

First group patients who vaccinated and measure the AMH before and up to 9 months after vaccination.

Treatment:

Biological: Vcinated

Infected patients by covid-19 and not vacinated

Description:

Second group patients who were infected by Covid-19 ant therefor were not vaccinated

Not infected nor vacinated

Description:

Ptients who who were not infected nor vacinated by Covid-19.