Impact of Dairy Products on Postprandial Inflammation

Agroscope Liebefeld-Posieux Research Station ALP

Status: Completed

Conditions: Inflammation; Nutritional Intervention; Obesity

Treatments: Other: consumption of test meal based on dairy products; Other: consumption of high fat test meal without dairy products; Other: consumption of high fat test meal with dairy products

Study type: Interventional

Funder types: Other

Identifiers

NCT01885416

NUTRICHIP-2

Details and patient eligibility

About

The study will quantitatively evaluate the systemic, postprandial inflammatory and metabolic response to the ingestion of three different meals in obese subjects. The administered meals will differ in the proportion of dairy products. Postprandial response will be monitored during 6 hours after meal consumption.

Enrollment: 21 patients

Sex: Male

Ages: 25 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• male
• BMI ≥ 20 kg/m2
• age 25-55 y
• informed consent

Exclusion criteria

• Physiological or psychological diseases
• Allergies to food or intolerance to high-fat meal
• Vegetarians
• Chronic intake of drugs
• Smokers
• Diabetes mellitus Type I and II
• Debilitating kidney diseases
• Debilitating liver diseases
• Clinically established coronary heart diseases
• Ingestion of vitamins or dietary supplements during the course of the study

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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21 participants in 3 patient groups

high fat meal without dairy products

Active Comparator group

Description:

high fat meal without dairy products

Treatment:

Other: consumption of high fat test meal without dairy products

high fat meal with additional milk

Experimental group

Description:

high fat meal with additional milk

Treatment:

Other: consumption of high fat test meal with dairy products

dairy product meal

Experimental group

Description:

dairy product meal

Treatment:

Other: consumption of test meal based on dairy products