Impact of Dexamethasone Added to Intra-articular Morphine and Bupivacaine for Post-operative Analgesia After Knee Arthroscopy

Ain Shams University

Status and phase

Completed

Phase 4

Conditions

Anesthesia

Treatments

Drug: group MD

Drug: group M

Study type

Interventional

Funder types

Other

Identifiers

NCT04790292

FMASU MS 20/2020

Details and patient eligibility

About

A randomized double-blinded clinical trial was carried out on 40 patients undergoing knee arthroscopy. Patients were divided randomly into two equal groups. All drugs used were injected intra-articularly at the end of arthroscopy. In the control group, patients were administered 10mg morphine added to bupivacaine 25mg. In the study group, patients were administered 10mg morphine and 8mg dexamethasone added to bupivacaine 25mg. Visual analog score for pain at rest and movement, time to first analgesic request, total analgesic consumption, duration of analgesia and adverse effects were recorded.

Enrollment

40 patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Minimum Age: 18 years Maximum Age: 65 years Sex: Both Gender Based: No Accepts Healthy Volunteers: No

Criteria:

Inclusion Criteria:

American Society of Anesthesiologists (ASA) physical status I and II
Scheduled for minor arthroscopic knee surgeries (meniscectomy, chondroplasty, minor ligament repair and diagnostic arthroscopy)

Exclusion Criteria:

American Society of Anesthesiologists (ASA) physical status above (II)
Undergoing major knee surgeries
History of allergies to any of the used drugs
History of diabetes mellitus
Contraindications of morphine use (e.g. asthmatic patient, chronic obstructive pulmonary disease, and addiction)