Impact of Diabetes Mellitus on Retinal Microvasculature in Patients Without Clinical Retinopathy Using Optical Coherence Tomography Angiography

Sohag University

Status: Completed

Conditions: Diabetic Retinopathy, DR

Treatments: Diagnostic Test: optical coherence tomography angiography

Study type: Observational

Funder types: Other

Identifiers

NCT06457295

Soh-Med-24-05-16MS

Details and patient eligibility

About

the aim of this study is to assess the impact of duration of DM on OCTA parameters in diabetic patients without clinical Diabetic retinopathy.

Enrollment: 200 patients

Sex: All

Ages: 40+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Type of DM: Type 2.
2. Fundus examination: no macular edema or other signs of clinical retinopathy

Exclusion criteria

1. Ocular history : any history of significant ocular injury or disease that could affect the retinal microvasculature such as retinal vascular occlusion, glaucoma, or vitreo-macular disease, as such conditions have also been noted to show sub-clinical OCTA changes [13, 14].
2. Fundus examination: macular edema or any other signs of clinical retinopathy

Trial design

200 participants in 4 patient groups

non-diabetic

Description:

patients who are above 40 years old and don't have diabetes

Treatment:

Diagnostic Test: optical coherence tomography angiography

diabetic (0-5y)

Description:

patients who are above 40 years old and have diabetes for less than 5 years

Treatment:

Diagnostic Test: optical coherence tomography angiography

diabetics (5-10y)

Description:

patients who are above 40 years old and have diabetes for 5-10 years

Treatment:

Diagnostic Test: optical coherence tomography angiography

diabetics (10y < )

Description:

patients who are above 40 years old and have diabetes for more than 10 years

Treatment:

Diagnostic Test: optical coherence tomography angiography