Impact Of Early Cognitive Rehabilitation On Functional Outcomes Following Moderate Traumatic Brain Injury

Amany Saadallah Hassan Mobarez

Status: Invitation-only

Conditions: TBI (Traumatic Brain Injury)

Treatments: Behavioral: Control group; Behavioral: early cognitive therapy program in addition to selected physical therapy program (positioning, chest care exercise).; Behavioral: selected physical therapy program (Chest care exercise, passive movement of the four limbs) in addition to early cognitive therapy program

Study type: Interventional

Funder types: Other

Identifiers

NCT06981897

TBI

Details and patient eligibility

About

Purpose of the study:

This study aims to detect the impact of early cognitive rehabilitation on functional outcomes with patients following moderate traumatic brain injury.

Full description

Intensive care unit (ICU) hospitalization saves lives but often costs ICU survivors, who often experience cognitive impairment and physical and functional disabilities. Early physical rehabilitation improves chances of regaining pre-hospital functional status, but early cognitive rehabilitation for these patients remains unexplored Traumatic brain injury occurs from violent blows or objects, causing physical and psychological effects. Signs may appear immediately or days later, affecting the brain's function and functioning . Traumatic Brain Injury (TBI) impacts health and quality of life, with unpredictable prognosis. Exercise is crucial for neuroplasticity and brain rewiring.The Glasgow Coma Scale, published in 1974, measures impaired consciousness in acute medical and trauma patients using eye-opening, motor, and verbal responses. It provides a clear, communicable picture of a patient's state.

The Rancho Los Amigos Scale (RLAS) is a medical assessment tool for individuals recovering from closed head injuries, including traumatic brain injuries. It evaluates cognitive and behavioral presentations as they emerge from coma, comparing patients' state of consciousness and reliance on assistance .

The Functional Independence Measure (FIM) is an 18-item assessment tool for evaluating patients' functional status in rehabilitation after stroke, traumatic brain injury, spinal cord injury, or cancer. It evaluates self-care, continence, mobility, transfers, communication, and cognition, with each item rated 1-7 .

Enrollment: 34 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Both Genders.
2. Moderate traumatic brain injury patients will be included with GCS score 9-12.
3. Patients' age 18 years old and more .
4. All patients must be medically stable post trauma.

Exclusion criteria

1. children under 18 years old .
2. Previous cerebral infarction and intracranial space-occupying lesions.
3. Patients with cancer and major underlying illnesses.
4. Patients with diffuse axonal damage.
5. Incomplete clinical and imaging data
6. Patient with other neurological deficits or orthopedic abnormalities that causing disability.
7. Patients with serious psychiatric pathology or mentally. -

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Sequential Assignment

Masking: None (Open label)

---

34 participants in 2 patient groups

study group

Experimental group

Description:

Seventeen Patients in study group will receive selected physical therapy program (Chest care exercise, passive movement of the four limbs) in addition to early cognitive therapy program

Treatment:

Behavioral: selected physical therapy program (Chest care exercise, passive movement of the four limbs) in addition to early cognitive therapy program

Behavioral: early cognitive therapy program in addition to selected physical therapy program (positioning, chest care exercise).

Behavioral: Control group

Control group

Experimental group

Description:

Seventeen Patients in control group will receive selected physiotherapy program only Chest care exercise, passive movement of the four limbs.

Treatment:

Behavioral: selected physical therapy program (Chest care exercise, passive movement of the four limbs) in addition to early cognitive therapy program

Behavioral: Control group