Impact of Early Mobilization on SAH Patients Physiological Parameters (MOBALPAH)

Assistance Publique - Hôpitaux de Paris

Status: Not yet enrolling

Conditions: Subarachnoid Hemorrhage

Treatments: Device: lung ultrasound; Device: clinical examination; Device: Transcranial Doppler; Device: near-infrared spectroscopy (NIRS)

Study type: Observational

Funder types: Other

Identifiers

NCT06286683

APHP231706

Details and patient eligibility

About

The aim of the study is to evaluate the physiological response to out-of-bed mobilization in patients admitted to the intensive care unit for subarachnoid hemorrhage. More specifically, the aim is to measure the impact on cerebral perfusion, lung aeration, cardiovascular and respiratory parameters.

Full description

In patients with subarachnoid hemorrhage, the mobilization strategy has been little studied. Several studies have already evaluated the consequences of mobilization in bed. Because of the deleterious consequences of prolonged bed rest, and in line with recommendations, practices have evolved towards early out-of-bed mobilization, which has shown benefits. However, the physiological consequences of out-of-bed mobilization have not yet been assessed. The aim of this study is to measure the impact of early out-of-bed mobilization of patients admitted for SAH on neuro-cardio-pulmonary physiological parameters.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Age ≥ 18 years

• Aneurysmal SAH
• Severity score World Federation Neurological Surgeons I to IV
• Secured aneurysm
• Eligible for their first early mobilization

Exclusion criteria

• Sedated patient
• Disturbed alertness, coma
• Unsecured aneurysm
• Patients under legal protection (guardianship, curatorship, safeguard of justice)

Trial design

100 participants in 1 patient group

Patients admitted to intensive care

Description:

Patients admitted to intensive care for aneurysmal subarachnoid hemorrhage (SAH) and eligible for their first out-of-bed mobilization

Treatment:

Device: near-infrared spectroscopy (NIRS)

Device: clinical examination

Device: Transcranial Doppler

Device: lung ultrasound