Impact of Embryo Cryopreservation on Birth Weight

University Hospital Center (CHU)

Status: Completed

Conditions: Infertility

Study type: Observational

Funder types: Other

Identifiers

NCT03989843

RECHMPL19_0306

Details and patient eligibility

About

Birth weight (BW) is higher after frozen embryo transfer (FET) than after fresh embryo replacement. No study has compared the BW of siblings conceived using the same oocyte/embryo cohort. The aim of this study was to determine whether the freezing-thawing procedure is involved in such difference.

Enrollment: 183 patients

Sex: Female

Ages: 18 to 43 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• sibling pairs where fresh embryo replacement resulting in a singleton live birth was followed by transfer of one or two frozen embryos from the same cohort that resulted in a singleton live birth, between May 2007 and June 2015.

Exclusion criteria

• Twin pregnancies and stillbirths were excluded. If the BW of at least one sibling was unknown, the pair was not included in the study.

Trial design

183 participants in 2 patient groups

Frozen embryo transfer

Description:

Frozen embryo transfer

Fresh embryo transfer

Description:

Fresh embryo transfer