Impact of Extubation Location After Surgery on Perioperative Times (Extub_Loca)

University Hospital, Clermont-Ferrand

Status: Completed

Conditions: Respiratory Failure; Surgery; Complication,Postoperative; Intubation; Extubation; Anesthesia

Treatments: Procedure: Extubation in operative room; Procedure: Extubation in post anesthesia care unit

Study type: Observational

Funder types: Other

Identifiers

NCT06249659

IRB-MTP_2022_04_202201100

Details and patient eligibility

About

The additional time required to awaken a patient is one of the main reasons for not extubating him or her in the operating room (OR). Conversely, transferring an intubated patient to recovery room (RR), prolonging the duration of anesthesia and intubation, in a limited environment in human resources, may lead to increased complications' rates. Little is known about those time lengths and complications rates.

Full description

The additional time required to awaken a patient is one of the main reasons for not extubating him or her in the operating room (OR). Conversely, transferring an intubated patient to recovery room (RR), prolonging the duration of anesthesia and intubation, in a limited environment in human resources, may lead to increased complications' rates. Little is known about those time lengths and complications rates. The primary objective was to evaluate the additional OR occupancy time associated with awakening and extubation. Secondary objectives were to assess the rate of post-extubation complications and the need for ventilatory support. This was a prospective multicenter observational study involving intubated patients who underwent surgeries in the operating theatres of the Montpellier and Clermont-Ferrand university hospitals. Anesthesia teams were asked to complete a form including data related to the patient, surgical procedure, anesthesia procedure (induction and recovery) and the occurrence of any complications during the procedure. A multivariate analysis was conducted on the full cohort, using a propensity score (IPTW, inverse probability of treatment weighting) to account for imbalances between groups.

Enrollment: 756 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult (older than 18 years old)
• Patients admitted to any operative room of participating centre for a surgical or endoscopic procedure under general anaesthesia requiring endo-tracheal intubation
• Subjects must be covered by public health insurance
• Written informed consent from the patient or proxy (if present) before inclusion or once possible when patient has been included in a context of emergency.

Exclusion criteria

• Patient extubated in intensive care unit
• Patient extubated during on-call hours (because of a reduced number of medical and paramedical staff)
• Patient extubated following cardiac surgery
• Refusal of study participation or to pursue the study by the patient
• Absence of coverage by the French statutory healthcare insurance system
• Protected person

Trial design

756 participants in 2 patient groups

Extubation in operative room

Description:

Patients are extubated in operative room after the end of surgery

Treatment:

Procedure: Extubation in operative room

Extubation in post anesthesia care unit

Description:

Patients are extubated in post anesthesia care unit, after transfer from operative room

Treatment:

Procedure: Extubation in post anesthesia care unit