Impact of FDG-PET/CT on Management of Patients with Native Valve Infective Endocarditis (PET-NAVIE)

University of Montreal

Status: Enrolling

Conditions: Native Valve Endocarditis; Infective Endocarditis

Study type: Observational

Funder types: Other

Identifiers

NCT04792281

MP-33-2020-2674

Details and patient eligibility

About

The proposed study is a multicentric prospective observational cohort study of patients with suspected NVE. The study population includes those with Possible IE according to the modified Duke criteria and investigated at one of the 6 participating sites which include 2 cardiac centers, the MHI and the IUCPQ, as well as 4 tertiary care centers, the Jewish General Hospital , the McGill University Health Centre and the CHUS.

Enrollment: 97 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years of age or older, capable to provide informed consent;
• Referred for a FDG-PET/CT study
• Classified as having Possible IE prior to FDG-PET/CT imaging;
• Patients must be able to tolerate the physical/logistical requirements of a PET/CT scan.

Exclusion criteria

• Subjects with prosthetic cardiac valve and/or CIED;
• Pregnant or breastfeeding female;
• Body mass index > 45 kg/m2.

Trial design

97 participants in 1 patient group

Patients with suspected native valve endocarditis