Impact of Flaxseed on the Syndrome Metabolic Inflammation

University of Sao Paulo

Status: Completed

Conditions: Metabolic Syndrome

Treatments: Other: Flaxseed or rice raw powder ingestion

Study type: Interventional

Funder types: Other

Identifiers

NCT02132728

HCRP 4244/2007

Details and patient eligibility

About

This study aims to evaluate the effects of enterolignanas of flaxseed on nutritional and inflammatory indicators in male workers of a food industry.

Enrollment: 52 patients

Sex: Male

Ages: 20 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Work in the manufacturing company in the city of Itu-SP.
• Have at least three of the following cardiovascular risk factors: waist circumference ≥ 90 cm; overweight or obese characterized by BMI ≥ 25 kg/m²; fasting total cholesterol ≥ 200 mg/dL, LDL- cholesterol ≥ 130 mg/dL and HDL-cholesterol < 40 mg/dL, triglycerides ≥ 150 mg/dL; glycemia ≥100 mg/dL; and hypertension characterized by systolic blood pressure ≥140 mm/Hg and/or diastolic blood pressure ≥ 90 mm/Hg.

Exclusion criteria

• Female gender

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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52 participants in 4 patient groups

Control group

No Intervention group

Description:

In the group with 11 volunteers, the control group did no change in normal food intake.

Flaxseed group

Experimental group

Description:

In this group with 14 volunteers, they received 50% carbohydrate, 31% fat, 19% protein and 60 g of flaxseed powder / day during the period of study.

Treatment:

Other: Flaxseed or rice raw powder ingestion

Rice and low carb group

Experimental group

Description:

In this group with 13 volunteers, they received 35% carbohydrate, 46% fat, 19% protein and 60g of raw rice powder / day during the period of study.

Treatment:

Other: Flaxseed or rice raw powder ingestion

Flaxssed and low carb group

Experimental group

Description:

In this group with 14 volunteers, they received 32% carbohydrate, 47% fat, 21% protein and 60 g of flaxseed powder / day during the period of study.

Treatment:

Other: Flaxseed or rice raw powder ingestion