Impact of General Anaesthetics on Excitability of the Peripheral Sensory Nerve

University of Zurich (UZH)

Status: Completed

Conditions: Scheduled for Surgery

Treatments: Behavioral: Nerve excitability measurement

Study type: Observational

Funder types: Other

Identifiers

NCT00696254

5-2008

Details and patient eligibility

About

The aim of this study is to investigate the effect of general anaesthetics on nerve excitability. We use the method of threshold tracking to measure selected parameters of nerve excitability.

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria: German speaking patients scheduled for surgery under general anaesthesia.

Weight 50 - 100 kg signed informed consent

Exclusion criteria: 1. known peripheral neuropathy 2. Diabetes mellitus 3. Neuro-psychiatric Diagnosis 4. pregnant/ breast-feeding women 5. congestive heart disease 6. more than 2 risk factors (out of 4) for PONV (female, non-smoker, known PONV, opioids postoperatively) 7. participants of other studies 8. inability of verbal expression