Impact of Genetic Polymorphisms on Dental Implant Loss

Ghent University Hospital (UZ)

Status: Completed

Conditions: Patients Treated by Means of 1 or More Dental Implants

Treatments: Procedure: oral examination; Procedure: Blood sample; Other: anamnesis

Study type: Interventional

Funder types: Other

Identifiers

NCT01274442

2010/771

Details and patient eligibility

About

Patients that may participate in this case-control study underwent dental implant surgery in the University Hospital in Ghent in 2004-2007.

According to one of our recent papers based on this patient group, 34/461 patients lost one or more implants. The goal is to invite these 34 patients, to update the anamnesis, to perform a brief clinical oral examination and to have a blood sample. The latter is necessary to identify relevant genetic polymorphisms of the patient that are associated with implant loss. Among the remaining patients that did not lose implants, another 34 'controls' will be invited for the same examinations.

Enrollment: 13 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Dental implant surgery in the University Hospital in Ghent in 2004-2007.
• Case: dental implant loss
• Control: no dental implant loss

Exclusion criteria

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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13 participants in 2 patient groups

CONTROL: no dental implants lost

Active Comparator group

Description:

Group of patients who received an implant during a dental implant surgery in the University Hospital in Ghent in 2004-2007, who did not lose their implants.

Treatment:

Procedure: Blood sample

Procedure: oral examination

Other: anamnesis

CASE: patients lost one or more implants

Experimental group

Description:

Group of patients who received an implant during a dental implant surgery in the University Hospital in Ghent in 2004-2007, but who lost one or more implants.

Treatment:

Procedure: Blood sample

Procedure: oral examination

Other: anamnesis