Impact of Germicidal Light

University of Iowa

Status: Withdrawn

Conditions: Operating Room Exposure to S. Aureus; Bacterial Transmission; S.Aureus Transmission; 90-day Postoperative Surgical Site Infections, Superficial and Deep

Treatments: Device: Germicidal lighting

Study type: Interventional

Funder types: Other

Identifiers

NCT03886337

201901773

Details and patient eligibility

About

Visible light at 405nm has been shown to be germicidal. The hypothesis is that use of this light (Indigo-Clean Lights) in operating rooms will reduce S. aureus transmission occurring within and between patients and reduce surgical site infections (SSIs). Investigators will evaluate a case-control study where patients undergoing surgery with the lights are matched with patients undergoing surgery without germicidal lights.

Full description

Operating room S. aureus exposure has been directly linked to postoperative infections and is therefore an important target for infection prevention. Visible light at 405nm has been shown to be germicidal. Investigators plan to install ambient, germicidal lighting (Indigo-Clean Lights) that uses this wavelength in 4 operating rooms. Patients will undergo surgery according to usual practice. Investigators will conduct a case-control study where patients undergoing surgery with the lights are matched with patients undergoing surgery without the germicidal lights. Patients will be matched by procedure then case duration then American Society of Anesthesiologists (ASA) physical status health classification. These patients will undergo infection surveillance. Infection surveillance will involve use of National Healthcare Safety Network (NHSN) checklists applied to patients who are positive for one or more of the initial screening criteria (elevated white blood cell count, fever (>38.4 degrees Celsius), office note documentation of infection, positive culture (sputum, blood, urine, wound, other body fluid), or anti-infective order within the 90 postoperative day period.

Sex: All

Ages: 18 to 120 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adult, at least 18 years old
• Adult patients undergoing orthopedic, cardiothoracic, gyn/onc, and neuro surgery and general anesthesia according to usual care with peripheral and/or central venous access.

Exclusion criteria

• Pediatric (<18 years old),
• Incarcerated, and/or
• Pregnant patients
• Undergoing surgery and/or without peripheral or central venous access.
• Undergoing surgery outside of the classifications above

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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0 participants in 2 patient groups

Control

No Intervention group

Description:

The control arm will be surgical care according to usual practice with usual ambient lighting

Treatment Arm

Experimental group

Description:

The treatment arm will include surgical care according to usual practice with germicidal ambient lighting

Treatment:

Device: Germicidal lighting