Impact of Hepatitis B Virus on Inflammatory Bowel Disease

Tanta University

Status: Enrolling

Conditions: Hepatitis B Virus; Inflammatory Bowel Disease (IBD)

Treatments: Other: History of IBD course and outcome in HBV patients

Study type: Observational

Funder types: Other

Identifiers

NCT06881238

36264PR979/12/24

Details and patient eligibility

About

The goal of this observational retrospective study is to assess the impact of hepatitis B virus (HBV) infection on the clinical course and outcomes of inflammatory bowel disease (IBD) in Egyptian patients.

Researchers will compare the IBD extent, location, severity, and behavior between IBD patients with and without HBV infection.

Participants will be subjected to history-taking (history of hospital admission and disease flare, surgical history, medication history, follow-up duration, and mortality), clinical examination, laboratory investigations, abdominal ultrasonography, and endoscopic examination.

Enrollment: 162 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male or female patients older than 18 years.
• Patients with IBD are diagnosed by clinical, radiological, endoscopic, and histological criteria.

Exclusion criteria

• Patients aged < 18 years
• Unwilling to participate in our study

Trial design

162 participants in 2 patient groups

IBD patients with positive HBV infection.

Description:

81 IBD patients with positive HBV infection.

Treatment:

Other: History of IBD course and outcome in HBV patients

IBD Patients with negative HBV infection

Description:

81 IBD Patients with negative HBV infection

Treatment:

Other: History of IBD course and outcome in HBV patients