Impact of HPV on a Cohort of Southern Italian Women: Epidemiological, Clinical, Morphological and Microbiological Features

University of Campania "Luigi Vanvitelli"

Status: Completed

Conditions: Cervix Cancer

Treatments: Diagnostic Test: Cervical biopsy

Study type: Interventional

Funder types: Other

Identifiers

NCT03959410

N.594

Details and patient eligibility

About

HPV is known to be the causal agent in the majority of cervical cancers. However, the role of the cervical bacterial microbiome in cervical cancer is not clear

Enrollment: 150 patients

Sex: Female

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women in fertile age

Exclusion criteria

• severe comorbidities

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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150 participants in 3 patient groups

HPV-positive patients

Active Comparator group

Description:

Patients who are positive for HPV DNA test

Treatment:

Diagnostic Test: Cervical biopsy

HPV-positive patients - Echinacea

Active Comparator group

Treatment:

Diagnostic Test: Cervical biopsy

HPV-positive patients - Standard

No Intervention group