Impact of Increasing BMI on the Success of Neuraxial Blocks in Class III Obese Parturients

Mariah Arif

Status: Completed

Conditions: Neuraxial Blocks

Treatments: Procedure: Neuraxial anesthesia

Study type: Observational

Funder types: Other

Identifiers

NCT07367386

MRC-01-24-905

Details and patient eligibility

About

This study seeks to compare the success rates, feto-maternal outcomes, and complications associated with different neuraxial blocks in Class III obese parturient undergoing cesarean section

Full description

This was a retrospective cohort study. The data was obtained from electronic medical records of the eligible participants.

Enrollment: 1,917 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age > or equal to 18 years
• BMI ≥ 45 kg/m²
• Gestational age ≥ 28 weeks

Exclusion criteria

• Age < 18 years
• BMI < 45 kg/m²
• History of venous thromboembolism or arterial disease (e.g., DVT, PE, angina, MI, or stroke)
• Severe active lung, cardiovascular, renal, or liver disorders; autoimmune disease; or hemoglobinopathies
• Hereditary or acquired thrombophilia (e.g., Factor V Leiden mutation or antithrombin deficiency)
• In utero fetal demise (IUFD)
• Failed operative vaginal delivery
• Cesarean for the second twin or multiple pregnancies (triplets or higher)
• IVF pregnancy
• Intraoperative bleeding>1500mL
• Emergency cesarean section (Category I)
• Presence of large uterine fibroid ≥10 cm

Trial design

1,917 participants in 1 patient group

Class III obese parturient

Description:

Class III obese parturient undergoing cesarean section under neuraxial block

Treatment:

Procedure: Neuraxial anesthesia

Procedure: Neuraxial anesthesia

Procedure: Neuraxial anesthesia