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Impact of Intensive Outpatient Rehabilitation on Non-Motor Patient-Reported Outcomes in Parkinson's Disease (INTENSO)

U

Università Politecnica delle Marche

Status

Completed

Conditions

Parkinson Disease

Treatments

Other: Multimodal rehabilitation training at low intensity
Other: Multimodal rehabilitation training at high intensity

Study type

Observational

Funder types

Other

Identifiers

NCT06695286
ID 101/2024, number 3054

Details and patient eligibility

About

This historical cohort study aims to evaluate the impact of different intensity rehabilitation protocols on the short and medium-term severity of non-motor symptoms in patients with Parkinson's Disease. One of the principal strengths of this study is that it is a real-life study, so it has a high external validity necessary to test the clinical effectiveness of these two types of training, which could have significant practical implications for rehabilitation in Parkinson's disease.

Enrollment

48 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • adults diagnosed with Idiopathic PD, Hoehn & Yahr stage ≥ 1 < 5, consecutive referral to the rehabilitation facility between 1 January 2014 and 31 December 2019 to receive outpatient physiotherapy treatment for the management of motor disability, specifically targeting gait, balance, or posture disorders;
  • completion of the course of rehabilitation treatment;
  • availability of Non-Motor Symptom Scale and Unified Parkinson's Disease Rating Scale, recorded before and after treatment and 6 plus or minus 1 months later

Exclusion criteria

  • diagnosis of any primary or secondary parkinsonism rather than PD
  • symptom onset since less than three years
  • any concomitant neurological disease (e.g. polyneuropathy, stroke, etc)
  • any other chronically disabling disease (e.g. severe heart, liver or kidney failure, cancer, psychiatric disorders, limb amputation, severe musculoskeletal or neuropathic pain)
  • changes in antiparkinsonian drug therapy during the whole study period
  • exposure to a course of physiotherapy during the 6 months preceding the study

Trial design

48 participants in 1 patient group

People with Parkinson's Disease consecutively referred to the outpatient rehabilitation facility
Description:
Single center historical cohort study of people with PD consecutively referred to the outpatient rehabilitation facility of a Center for Diagnosis and Treatment of Movement Disorders, based in a university hospital in Italy.
Treatment:
Other: Multimodal rehabilitation training at high intensity
Other: Multimodal rehabilitation training at low intensity

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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