Impact of Maternal Supplementation With Dual Megadose of Vitamin A

Instituto Materno Infantil Prof. Fernando Figueira

Status and phase: Completed; Phase 3; Phase 2

Conditions: Vitamin A Deficiency; Hypovitaminosis

Treatments: Dietary Supplement: vitamin A; Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT00742937

IMIPVITA-001

Details and patient eligibility

About

The purpose of this study is to evaluate the effect of maternal supplementation with 400,000 IU of oral retinol palmitate in the post-partum, the nutritional situation of the binomial mother-child, on growth and morbidity of children in breastfeeding in the first six months of life.

Full description

The effect will be assessed by the milk and blood.

Enrollment: 239 patients

Sex: Female

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Pregnant low-risk obstetric

Exclusion criteria

• Premature birth
• Newborn babies with birth defects and / or other serious diseases

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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239 participants in 2 patient groups, including a placebo group

A

Placebo Comparator group

Description:

After birth the women will receive one capsule 200,000 UI of retinol palmitate (vitamin A)plus vitamin E and eight days after delivery the second capsule of vitamin E will be administer.

Treatment:

Dietary Supplement: Placebo

B

Experimental group

Description:

After birth the women will receive one capsule 200,000 UI of retinol palmitate (vitamin A)plus vitamin E and eight days after delivery the second capsule of 200,000 UI of retinol palmitate (vitamin A)plus vitamin E will be administer.

Treatment:

Dietary Supplement: vitamin A