Impact of MultiPoint Pacing Technology in CRT Patients With Reduced RV-to-LV Delay (IMAGE-CRT)

Monaldi Hospital

Status: Unknown

Conditions: Cardiac Resynchronization Therapy

Study type: Observational

Funder types: Other

Identifiers

NCT02713308

MP001

Details and patient eligibility

About

Observational, retrospective and perspective study with acute and chronic endpoints

Full description

Study to assess the benefit from Multipoint Pacing (MPP) in presence of RV-to-LV delay<80ms in terms of rate of CRT responder patients at 6 Months from CRT-D system implantation

Enrollment: 248 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Indication to CRT-D system implantation according to current guidelines or CRT-D system already implanted in patient scheduled to CRT-D system implantation according to current guidelines

Exclusion criteria

• Right Bundle Branch Block
• Severe Irreversible Renal Failure (eGFR<30)
• NYHA IV
• Atrio-Ventricular Block above the 1st grade
• Prosthetic Valves
• Atrial Fibrillation at implantation

Trial design

248 participants in 2 patient groups

Group1-CRT

Description:

Patients with RV-to-LV delay≥80ms, CRT standard programming (single-point)

Group2-MPP

Description:

Patients with RV-to-LV delay\<80ms, CRT programming with MPP (multi-point)