Impact of Muscular Fatigability on Spastic Co-contractions After Stroke Patients (COCON)

University Hospital, Lille

Status: Completed

Conditions: Spasticity, Muscle; Stroke; Muscle Fatigue; Gait, Hemiplegic

Treatments: Procedure: Muscle fatigue

Study type: Interventional

Funder types: Other

Identifiers

NCT03342820

2017_A01605-48 (Other Identifier)

2016_50

Details and patient eligibility

About

This study evaluates the effects of an isokinetic fatigue protocol of the quadriceps on the amount of co-contractions of this last with the hamstrings during a maximal isometric flexion movement in hemiparetic stroke patients.

The effect of such a protocol on gait parameters and spasticity of the quadriceps will be evaluated also.

Enrollment: 30 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age between 18 and 80y
• Hemiparesis after a first-ever stroke > 3 months
• Spasticity of the quadriceps muscle
• Quadriceps strength at least at 3/5 (MRC testing)
• Subject able to walk at least 2min without rest
• Informed consent
• Social security affiliation

Exclusion criteria

• Severe comprehension troubles (language, cognitive or psychiatric disorders)
• History of previous stroke, locomotor or other neurological disorders
• Locomotor troubles affecting the paretic arm
• Contraindication to efforts : cardiac insufficiency, severe aortic valvular stenosis, recent heart failure, non treated high blood pressure, severe peripheral arterial disease
• Pregnancy or breastfeeding
• Adult subject to guardianship

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

Quadriceps muscle fatigue

Experimental group

Description:

Quadriceps muscle fatigue

Treatment:

Procedure: Muscle fatigue