Impact of Nebivolol on Central Aortic Pressure

Creighton University

Status: Withdrawn

Conditions: Central Aortic Pressure

Treatments: Drug: Nebivolol; Drug: Metoprolol

Study type: Interventional

Funder types: Other

Identifiers

NCT01051947

08-15168

Details and patient eligibility

About

A randomized, cross-over, single-blind study to compare the effects of nebivolol and metoprolol on central aortic pressure and peripheral brachial pressure in patients with stable cardiovascular disease.

Sex: All

Ages: 45 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects with history of hypertension
• Subjects who have received metoprolol for a minimum of 3 months

Exclusion criteria

• Patients who have had an acute myocardial infarction, coronary revascularization or who have been hospitalized for heart failure or cardiac arrhythmia in the past 6 months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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0 participants in 2 patient groups

Nebivolol

Experimental group

Description:

Nebivolol therapy for 2-6 weeks depending on blood pressure readings

Treatment:

Drug: Nebivolol

Metoprolol

Experimental group

Description:

Metoprolol therapy for 2-6 weeks depending on blood pressure readings

Treatment:

Drug: Metoprolol