Impact of Neurally Adjusted Ventilator Assist (NAVA) Mode on Patient Ventilator Asynchrony Using Non-invasive Ventilation (NAVA-NIV)

Pierre and Marie Curie University

Status: Completed

Conditions: Weaning Period

Treatments: Other: Device: Neurally Adjusted Ventilatory Assistance

Study type: Observational

Funder types: Other

Identifiers

NCT01280760

UPMC

Details and patient eligibility

About

Non-invasive ventilation (NIV) has been proposed to reduce the incidence of ventilatory dysfunction following mechanical ventilation weaning. However, the nasogastric tube reduces the airtightness of the facial mask used to perform non-invasive ventilation and induces air leaks. The presence of leaks at the patient-mask interface can increase the risk of patient-ventilator asynchrony, which in turn leads to increase patient discomfort. Neurally adjusted ventilatory assist (NAVA)could contribute to decreasing asynchrony. Its principle is to record the diaphragmatic electrical activity and to control the ventilator. The investigators hypothesized driving the ventilator based on a neural signal (diaphragm electrical activity) would reduce patient-ventilator asynchronies in NIV

Enrollment: 16 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Patients with increased risk of post-extubation ventilatory dysfunction following invasive mechanical ventilation weaning.

Exclusion criteria

• Contra-indication to non-invasive ventilation
• Pregnancy

Trial design

16 participants in 1 patient group

Non invasive ventilation

Description:

Non-invasive ventilation after invasive mechanical ventilation weaning

Treatment:

Other: Device: Neurally Adjusted Ventilatory Assistance