Impact of Neurological Diseases on the Prognosis of Bullous Pemphigoid: A Retrospective Study of 178 Patients

CHU de Reims

Status: Completed

Conditions: Bullous Pemphigoid

Treatments: Other: Data record

Study type: Observational

Funder types: Other

Identifiers

NCT03320798

2016Ao004

Details and patient eligibility

About

Bullous pemphigoid affects mainly elderly patients. It is often associated with neurologic disorders, which represent a major risk factor of the disease

Full description

The aim was to determine whether neurologic disorders, especially dementia, influences outcome and mortality of patients with bullous pemphigoid.

Enrollment: 178 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• patients presenting bullous pemphigoid using the following criteria: clinical features typical of BP with presence of at least three out of four well-established criteria of Vaillant et al., subepidermal blister on skin biopsy and deposits of IgG and/or C3 in a linear pattern along the epidermal basement membrane zone by direct IF
• patients consulting at dermatology department of Reims Teaching Hospital (France) between 1997 and 2011

Trial design

178 participants in 1 patient group

group "Bullous pemphigoid"

Description:

Patients consulting at dermatology department of Reims Teaching Hospital for bullous pemphigoid between 1997 and 2011.

Treatment:

Other: Data record