Impact of Number of Rank of B-lactam Antibiotics on Emergence on Multidrug Resistant Bacteria (INOR Blact)

Centre Hospitalier Universitaire de Besancon

Status: Unknown

Conditions: Resistant Infection; Bacterial Resistance; Antibiotic Resistant Infection; Beta Lactam Resistant Bacterial Infection

Treatments: Procedure: number of Beta lactam class prescription for the same infection

Study type: Observational

Funder types: Other

Identifiers

NCT03752476

Dossot

Details and patient eligibility

About

This study evaluates the impact of rank of Beta lactam antibiotics on emergence of mutlidrug resistant bacteria colonization in intensive care

It's retrospective case controle study. Cases are colonized patient by multidrug resistant bacteria hospitalized in intensive care during the fist hospitalization in intensive care. Temoin are patients with the same characteristics than case but no colonized by multidrug resistant bacteria.

Full description

The emergence of multidrug resistant is a wordwide problem. B lactam resistant increase. The antibiotic prescription impact this problem.

B lactam antibiotic is prescribed everyday in intensive care unit. The switch of antibiotic is common. Antibiotic classes inclue a lot of rank with different spectum that impact the occurrence of resistant.

Enrollment: 1,300 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• all patient hospitalized more than 48 hours in intensive care unit in Besançon between january 2016 and december 2017

Exclusion criteria

• patient under guardianship
• patient allergic to Beta lactam
• colonization with mutidrug resistant the first week of hospitalization in intensive care unit

Trial design

1,300 participants in 2 patient groups

case

Description:

Patients are colonized patient by antimicrobial bacteria hospitalized in intensive care during the fist hospitalization in intensive care during 2016-2017.

Treatment:

Procedure: number of Beta lactam class prescription for the same infection

control

Description:

Patients aren't colonized patient by antimicrobial bacteria hospitalized in intensive care during the fist hospitalization in intensive care during 2016-2017.

Treatment:

Procedure: number of Beta lactam class prescription for the same infection