Impact of OCT Imaging on Decision Making During PCI in ACS Patients

Assiut University

Status: Completed

Conditions: Acute Coronary Syndrome

Treatments: Device: OCT-guided PCI

Study type: Observational

Funder types: Other

Identifiers

NCT04444037

OCT in ACS patients

Details and patient eligibility

About

Optical coherence tomography (OCT) provides valuable information to guide percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS) regarding lesion preparation, stent sizing, and stent optimization.

Full description

OCT can be used in acute coronary syndrome (ACS). ACS has more complex culprit lesion morphologies and larger extent of coronary atherosclerosis compared with stable coronary artery disease. The detailed vascular information obtained by OCT may impact PCI in ACS, and which may improve acute results and late outcomes of PCI. Stent expansion immediately after PCI is a strong predictor of late outcomes of PCI, and it is associated with late clinical outcomes in many previous trials.

Enrollment: 390 patients

Sex: All

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients presented with acute coronary syndrome.
• PCI was done to them with stent implantation.

Exclusion criteria

• Multivessel PCI at the index procedure.
• Patients with ACS due to graft failure post CABG.
• Patients treated with no stent implantation.

Trial design

390 participants in 2 patient groups

OCT-guided PCI

Description:

PCI procedure was done with intra-coronary imaging OCT.

Treatment:

Device: OCT-guided PCI

Angiography-guided PCI

Description:

PCI procedure was done without any intra-coronary imaging assistance, guided by angiography alone