Impact of OCT on Outcomes in AMI

Capital Medical University

Status: Unknown

Conditions: Acute Myocardial Infarction

Treatments: Device: OCT guided coronary intervention

Study type: Observational

Funder types: Other

Identifiers

NCT05266547

BeijngLH

Details and patient eligibility

About

This protocol describes a retrospective, single-center study intended to test the impact of optical coherence tomography(OCT) on long term clincical outcomes in patients with acute myocardial infarction(AMI). All the patients will be followed by intracoronary OCT at medium follow-up of 3 years.

Enrollment: 1,600 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age≥18 years old
• Patients undergo cardiac catheterization and percutaneous coronary intervention(PCI) for AMI(STEMI or NSTEMI) ST-segment elevation myocardial infarction was defined according to the universal definition of myocardial infarction, symptoms onset≤ 24h.NSTEMI was defined as elevated troponin levels and the absence of ST elevation at the time of diagnosis, PCI was performed within 24hours after symtoms onset.
• Sufficient quality of the OCT recording allowing for CoreLab analysis.

Exclusion criteria

• ostial of Left main disease
• Cardiogenic shock or severe hemodynamic instability
• Severe renal insufficiency (creatinine clearance ≤30 mL/min)
• Bacteraemia or septicaemia
• Severe coagulation disorders
• Patients with life expectancy less than 1 year
• Patients who refuse to sign the informed consent form

Trial design

1,600 participants in 2 patient groups

OCT guided group

Treatment:

Device: OCT guided coronary intervention

angiography guided group

Treatment:

Device: OCT guided coronary intervention