Impact of Oligonol to Cardiometabolic Risk and Muscular Health

National Yang Ming Chiao Tung University

Status

Completed

Conditions

Quality of Life

Muscle Weakness

Muscle Loss

Treatments

Dietary Supplement: Placebo

Dietary Supplement: Oligonol intake

Study type

Interventional

Funder types

Other

Identifiers

NCT03788577

2018-05-004B

Details and patient eligibility

About

This project will mainly focus on Middle and old-aged adults, and examine whether Cardiovascular and metabolic risks can be reduced. In the meanwhile, this project will develop strategies for improving muscle loss , muscle strength decline, and the quality life of the elderly.

Full description

Cardiovascular diseases are common among the elder. However, previous researches mainly focus on observational research or small scale clinical trial, and the subjects are mainly youth. Therefore, this project hope to understand whether Oligonol can reduce Cardiovascular and metabolic risks among senior adults. Consequently,improve muscle loss muscle strength decline, quality of old adults life. This project design may potentially develop new strategies for curing Sarcopenia as well.

Enrollment

120 patients

Sex

All

Ages

50+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

People who aged more than 50 years
Patients with following characteristics:
feeling loss in activity.
detecting decline in self's walking speed.
feeling tired of doing everything.
having fallen down last year.
People can accept undergoing MRI
People willing to follow the program and cooperate with us for following tracking.
People who are neither vegan nor vegetarian

Exclusion criteria

Walking speed less than 0.3m/s
People with any disease affecting their limbs, including:
having fracture on limbs in the past 6 months.
having severe arthritis in the past 6 months
any other whom PI recognized as weak control of their nervous system( e.g.: Parkinson's disease and stroke).
People with intermittent limp caused by peripheral artery diseases
People with weak control of mental disorder
People with weak control of Cardiopulmonary disease
People with weak control of Malignant tumor
People with weak control of kidney diseases (GFR < 30 mL/min/1.73 m2 for at least 3 months)
People with visual impairment and hearing disorder who cannot complete the program.
People who are unable to undertake MRI
Any other condition that PI recognized as not suitable.