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Impact of Omega 3 in Treatment of Inappropriate Sinus Tachycardia

B

Benha University

Status

Completed

Conditions

Treatment
Omega 3
Inappropriate Sinus Tachycardia

Treatments

Drug: Omega 3
Other: Standard follow-up

Study type

Interventional

Funder types

Other

Identifiers

NCT07138131
MD 11-4-2023

Details and patient eligibility

About

This study aimed to evaluate the effect of omega-3 supplementation on heart rate (HR) control and heart rate variability (HRV) in children with inappropriate sinus tachycardia (IST).

Full description

Inappropriate sinus tachycardia (IST) is a is a common disease of the autonomic nervous system in children in which tachyarrhythmia characterized by a persistent increase in resting sinus rate or disproportionate elevation of heart rate (HR) with minimal physiological effort accompanied by wide ranging symptoms including palpitations, fatigue, presyncope, and exercise intolerance it could cause lead to total disability in severe cases .it also takes a chronic course with Significant adverse effects on quality of life.

Enrollment

60 patients

Sex

All

Ages

12 to 16 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age from 12 to 16 years.
  • Both sexes.
  • Patients diagnosed with inappropriate sinus tachycardia (IST).
  • Patients with resting heart rate (HR) ≥100 bpm (sitting) and/or 24-hour average HR ≥90.

Exclusion criteria

  • Structural heart disease.
  • Patients receiving antiarrhythmic medication.
  • Patients with a prior history of arrhythmias such as paroxysmal supraventricular tachycardia (PSVT) or sick sinus syndrome, or orthostatic hypotension.
  • Secondary conditions such as anemia, infection, or hyperthyroidism.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

60 participants in 2 patient groups

Group A
Experimental group
Description:
Patients received omega-3 supplementation for 3 months.
Treatment:
Drug: Omega 3
Group B
Active Comparator group
Description:
Patients received standard follow-up without treatment.
Treatment:
Other: Standard follow-up

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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