Impact of Oral Phosphorus Supplements on the 6-month Change in FGF23 Levels in Anorexic Adolescents Suffering From Undernutrition. (IPSAASU)

Centre Hospitalier Universitaire, Amiens

Status: Unknown

Conditions: Malnutrition

Study type: Observational

Funder types: Other

Identifiers

NCT02812134

PI2015_843_0006

Details and patient eligibility

About

Fibroblast growth factor 23 (FGF23) is a recently discovered phosphaturic hormone produced by osteocytes. It is involved in phosphate-calcium metabolism (via its phosphaturic action and inhibition of 1,25-OH vitamin D).

There are no published studies on the role of FGF23 in undernourished anorexic adolescents taking oral phosphorus supplements.

Enrollment: 30 estimated patients

Sex: All

Ages: 11 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adolescents aged from 11 to 17
• Follow-up or hospitalisation for anorexia
• Overt undernutrition (clinical signs of undernutrition, body mass index and the Waterlow index)
• Social security coverage

Exclusion criteria

• Known pre-existing renal disorders
• Known constitutional disorders of phosphate-calcium metabolism
• Adult patients, legal guardianship, incarceration

Trial design

30 participants in 1 patient group

anorexic