Impact of PD1-lymphocytes in Bronchoalveolar Lavage of Patients With Lung Cancer

University of Vienna

Status: Unknown

Conditions: Lung Cancer

Treatments: Diagnostic Test: bronchoalveolar lavage

Study type: Observational

Funder types: Other

Identifiers

NCT04827667

Version 1 20.04.2020

Details and patient eligibility

About

The aim of this trial is to assess PD1-lymphocytes in bronchoalveolar lavage in patients with lung cancer, ILD and asthma.

Full description

In this trial, 20 patients with lung cancer, 10 patients with asthma and 10 patients with interstitial lung disease who have to undergo bronchocospy for medical reasons are enrolled. In each patient, bronchoalveolar lavage is performed to assess PD1-lymphocytes.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age >18 years
• patients with lung cancer, asthma or ILD and indication for bronchoscopy for medical reasons
• Ability to provide informed consent

Exclusion criteria

• acute excacerbation in patients with asthma or ILD
• endoluminal tumor growth or penumonia in patients with lung cancer

Trial design

40 participants in 3 patient groups

Patients with lung cancer

Description:

In lung cancer patients with indication for bronchoscopy, bronchoalveolar lavage is performed to assess PD1-lymphocytes.

Treatment:

Diagnostic Test: bronchoalveolar lavage

Patients wiht interstitial lung disease

Description:

In patients with interstitial lung disease with indication for bronchoscopy, bronchoalveolar lavage is performed to assess PD1-lymphocytes.

Treatment:

Diagnostic Test: bronchoalveolar lavage

Patients with asthma

Description:

In patients with asthma with indication for bronchoscopy, bronchoalveolar lavage is performed to assess PD1-lymphocytes.

Treatment:

Diagnostic Test: bronchoalveolar lavage