Impact of Percutaneous Closure of the Left Atrial on the Maximum Proto-diastolic Speed of the Mitral Ring Measured by Tissue Doppler (ACTIFER)

Ramsay Générale de Santé

Status

Unknown

Conditions

Left Atrial Closure

Tissue Doppler

Treatments

Procedure: Trans thoracic echocardiography

Study type

Interventional

Funder types

Other

Identifiers

NCT05150366

2020-A02663-36

Details and patient eligibility

About

The main objective is to demonstrate the equivalence, before and after the percutaneous closure of the left atrial procedure, of the maximum proto-diastolic velocity of the lateral mitral annulus (e 'lat) measured by tissue Doppler. Patients with AF at high embolic risk and presenting a formal and definitive contraindication to anticoagulants having been operated on for percutaneous closure of the left atrial by St Jude AMULET device, considering an equivalence margin of 1 cm / sec.

Enrollment

48 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Man or woman over 18 years-old
Patient with paroxysmal AF at high embolic risk (CHA2DS2Vasc score ≥ 4) and presenting a formal and definitive contraindication to anticoagulants
Patient scheduled for percutaneous closure of the left auricle by St Jude AMULET device
Patient in sinus rhythm
Subject affiliated or beneficiary of a social security scheme
Patient having signed the informed consent

Exclusion criteria

Patient participating in another clinical study
Patient in permanent ACFA
Patient with a mitral prosthesis (biological or mechanical),
Patient with a history of mitral annuloplasty
Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision;
Pregnant, breastfeeding or parturient woman;
Patient hospitalized without consent.