Impact of Perioperative Shedding of the Endothelial Glycocalyx on Short-term Postoperative Complication in Patients Undergoing Robot-assisted Esophagectomy

Yonsei University

Status: Completed

Conditions: Robotic Esophagectomy

Study type: Observational

Funder types: Other

Identifiers

NCT03699878

4-2018-0773

Details and patient eligibility

About

The aim of this study was to determine whether changes in serum levels of syndecan-1 before and after surgery, which is an index related to injury of the endothelial glycocalyx layer, are associated with postoperative short-term complications and mortality in patients undergoing robotic esophagectomy.

Enrollment: 221 patients

Sex: Female

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. patients 20 years or older who undergo robotic esophagectomy

Exclusion criteria

1. Emergency surgery
2. If the subject includes a person who can not read the written consent (eg, illiterate, foreigner, etc.)
3. Chronic kidney disease (eGFR <30 mL / min / 1.73 m2)
4. Pregnant and lactating women
5. Use of oral anticoagulants

Trial design

221 participants in 1 patient group

patients undergoing robotic esophagectomy

Description:

Patients 20 years or older who undergo robotic esophagectomy