Impact of Persistent Microvascular Obstruction by Cardiac Magnetic Resonance on Prognosis for ST-segment Elevation Myocardial Infarction (IMCOME)

Chinese PLA General Hospital (301 Hospital)

Status: Completed

Conditions: ST Elevation (STEMI) Myocardial Infarction

Study type: Observational

Funder types: Other

Identifiers

NCT06759532

Z-2017-26-2202-2 (Other Grant/Funding Number)

Persistent MVO on prognosis

Details and patient eligibility

About

The aims of the study were to evaluate the predictive value of persistent microvascular obstruction (MVO) by cardiac magnetic resonance for main adverse cardiac events in ST-segment elevation myocardial infarction patients.

MVO in the acute phase of myocardial infarction has been considered to be strong predictor of a poor prognosis. We plan to explore the relationship between persistent MVO and the long-term prognosis of patients with STEMI. We made hypothesis that patients with persistent MVO have a poor prognosis.

Enrollment: 344 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ST-segment elevation myocardial infarction undewent primary percutaneous coronary intervention

Exclusion criteria

• contraindications for cardiac magnetic resonance
• severe heart failure
• previous myocardial infarction.

Trial design

344 participants in 3 patient groups

Without MVO group

Description:

STEMI patients without MVO both in the acutephase and chronic phase of myocardial inarction

with transient MVO group

Description:

STEMI patients with MVO only in the acutephase of myocardial inarction

with persietent MVO group

Description:

STEMI patients without MVO both in the acutephase and chronic phase of myocardial inarction