Impact of Platelet Activation in Intracranial Aneurysm Rupture Risk - PLAQRAN

Fondation Ophtalmologique Adolphe de Rothschild

Status: Active, not recruiting

Conditions: Intracranial Aneurysms; Ruptured Aneurysm

Treatments: Other: Collection of blood sample in aneurysm

Study type: Observational

Funder types: NETWORK

Identifiers

NCT03408379

MMI_2017_27

Details and patient eligibility

About

Sub arachnoid hemorrhage consecutive to intracranial aneurysm rupture is a devastating disease. Predictors of intracranial aneurysm rupture are limited and focus mainly on size and location. Platelet activation may have a deleterious role on aneurysm rupture. The assumption is that patients with ruptured intracranial aneurysm will present a higher rate of platelet activation compared to patients with non ruptured aneurysms.

Enrollment: 230 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient aged 18 and over
• Patient presenting a single or multiple aneurysm
• Patient presenting an intracranial aneurysm for which an intervention is planned (endovascular treatment or surgery) : elective intervention for an unruptured aneurysm or emergency surgery for a broken aneurysm

Exclusion criteria

• Pregnant or breast feeding woman
• Patient benefiting from legal protection measures