Impact of Positive & Negative Lens-Induced Defocus on Contrast-Sensitivity in Myopic & Non-Myopic Adults

Superior University

Status: Active, not recruiting

Conditions: Myopia

Treatments: Diagnostic Test: Negative Lens-Induced Defocus Using Spectacle Lenses (-2.00 D) for Myopic Participants; Combination Product: Positive Lens-Induced Defocus Using Spectacle Lenses (+2.00 D) for Non-Myopic Participants; Diagnostic Test: Positive Lens-Induced Defocus Using Spectacle Lenses (+2.00 D) for Myopic Participants; Combination Product: Negative Lens-Induced Defocus Using Spectacle Lenses (-2.00 D) for Non-Myopic Participants

Study type: Interventional

Funder types: Other

Identifiers

NCT06753032

MSRSW/Batch-Fall22/750

Details and patient eligibility

About

examines the influence of lens-induced defocus on contrast sensitivity-a crucial aspect of visual performance.Each participant experiences both positive and negative defocus through different lenses, with measurements taken for contrast sensitivity using the Pelli-Robson chart. Outcomes are evaluated at baseline, 2 weeks, and 4 weeks to understand the effect of defocus over time.

Full description

Additional data on symptoms like visual fatigue and computer vision syndrome are gathered using the Visual Fatigue Questionnaire (VFQ) and the Computer Vision Syndrome Questionnaire (CVS-Q), respectively. This study's findings could be instrumental in refining optical treatments, offering insights into how defocus impacts visual function across refractive conditions. Results may ultimately benefit optometric practices by guiding lens prescriptions for improved contrast sensitivity and quality of life for myopic and non-myopic individuals alike.

Enrollment: 36 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults aged 18 to 50 years.
• Participants with a confirmed diagnosis of myopia or non-myopia.
• Best corrected visual acuity of 20/30 or better.
• No history of ocular surgery or significant ocular disease.
• Informed consent was obtained.

Exclusion criteria

• Individuals with a history of systemic diseases affecting vision (e.g., diabetes, hypertension).
• Presence of binocular vision anomalies or strabismus.
• Pregnant or nursing women.
• Any current use of medications affecting visual function (e.g., medications causing visual side effects).

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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36 participants in 4 patient groups

interventional group

Experimental group

Treatment:

Diagnostic Test: Positive Lens-Induced Defocus Using Spectacle Lenses (+2.00 D) for Myopic Participants

Interventional group II

Experimental group

Treatment:

Diagnostic Test: Negative Lens-Induced Defocus Using Spectacle Lenses (-2.00 D) for Myopic Participants

Interventional group III

Active Comparator group

Treatment:

Combination Product: Positive Lens-Induced Defocus Using Spectacle Lenses (+2.00 D) for Non-Myopic Participants

Interventional group IV

Active Comparator group

Treatment:

Combination Product: Negative Lens-Induced Defocus Using Spectacle Lenses (-2.00 D) for Non-Myopic Participants