Impact of Preemptive Intravenous Ibuprofen on Intraoperative Analgesia in Third Molar Teeth

Erzincan University

Status: Unknown

Conditions: Intraoperative Analgesia; Preemptive Intravenous Ibuprofen

Treatments: Drug: intrafen 800 mg; Other: plasebos; Drug: arveles

Study type: Interventional

Funder types: Other

Identifiers

NCT03170726

ERZINCAN UNIVERSITY 9

Details and patient eligibility

About

This study was planned to evaluate the analgesic efficacy of preemptive intravenous (iv) ibuprofen on pain occurring during and after the mandibular third molar surgeon

Enrollment: 60 estimated patients

Sex: All

Ages: 20 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who are to be elected third molar tooth extraction
• Patients between the ages of 20-35
• Patients who are symptomatic
• Third molar tooth angular or horizontal settled patients

Exclusion criteria

• Patients who refuse to participate in the study
• Patients under 20 years old, over 35 years old
• Patients who are allergic to known non-steroidal anti-inflammatory drugs
• Pregnant patients
• Patients with severe liver failure,
• patients with severe renal insufficiency

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 3 patient groups, including a placebo group

arveles

Active Comparator group

Description:

Ibuprofen 800 mg in normal saline 150 cc and dexketoprofen (50 mg) before operation will be given in 30 minutes

Treatment:

Drug: arveles

Other: plasebos

Drug: intrafen 800 mg

intrafen

Active Comparator group

Description:

intrafen 800 mg in normal saline 150 cc before operation will be given in 30 minutes

Treatment:

Drug: arveles

Other: plasebos

Drug: intrafen 800 mg

plasebos

Placebo Comparator group

Description:

150 cc normal saline will be given in 30 minutes during preoperative period

Treatment:

Drug: arveles

Other: plasebos

Drug: intrafen 800 mg