Impact of Preemptive Intravenous Ibuprofen on Postoperative Edema and Trismus in the Third Molar Teeth

Erzincan University

Status: Unknown

Conditions: Edema; Trismus

Treatments: Other: placebos; Drug: arveles; Drug: intrafen

Study type: Interventional

Funder types: Other

Identifiers

NCT03170713

ERZINCAN UNIVERSITY 10

Details and patient eligibility

About

this study was planned to investigate the antiinflammatory activity of preemptive intravenous ibuprofen on inflammatory complications such as edema and trismus after third molar tooth surgery

Enrollment: 60 estimated patients

Sex: All

Ages: 20 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Elective 3. Molar tooth extraction
• Patients between the ages of 20-35
• Patients who are symptomatic
• 3. Molar tooth angular or horizontal settled patients

Exclusion criteria

• Patients who refuse to participate in the study
• Patients under 20 years old, over 35 years old
• Patients who are allergic to known non-steroidal anti-inflammatory drugs
• Pregnant patients
• Patients with severe hepatic insufficiency
• Patients with severe renal insufficiency

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 3 patient groups, including a placebo group

arveles

Active Comparator group

Description:

800 mg ibuprofen and 50 mg arveles in 150 cc normal saline before operation will be given in 30 minutes.

Treatment:

Drug: intrafen

Drug: arveles

Other: placebos

intrafen

Active Comparator group

Description:

intrafen 800 mg in 150 cc normal saline before operation will be given in 30 minutes.

Treatment:

Drug: intrafen

Drug: arveles

Other: placebos

placebos

Placebo Comparator group

Description:

Pre-operative 150 cc normal saline will be delivered in 30 minutes

Treatment:

Drug: intrafen

Drug: arveles