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Impact of Preoperative Frailty and Cognitive Impairment on Postoperative Outcomes in Elderly Cardiac Surgery Patients

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Yonsei University

Status

Completed

Conditions

Cardiovascular Diseases

Study type

Observational

Funder types

Other

Identifiers

NCT06330532
4-2023-1526

Details and patient eligibility

About

This is a retrospective study of patients aged 65 years and older who underwent cardiac and aortic surgery between March 5, 2021 and October 12, 2022 in the operating room of Severance Cardiovascular Hospital to determine the impact of physical frailty as well as nutritional status, emotional dysregulation, and cognitive dysfunction on postoperative outcomes. Physical frailty will be determined by the Clinical Frailty Scale, handgrip strength, and nutritional status, cognitive dysfunction will be determined by the K-MMSE and K-MoCA administered at the preoperative interview, and emotional dysregulation will be determined using the SGDS-K. These were measured during the pre-anesthesia evaluation and only results from patients who agreed to be tested will be used. Nutritional status will be analyzed based on blood test values measured within one month of surgery.

Enrollment

447 patients

Sex

All

Ages

65+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • 65-year-old patients undergoing surgery for heart and aortic disease, who completed physical (Clinical Frailty scale, Handgrip strength), cognitive(K-MoCA, K-MMSE), and emotional (SGDS-K) functioning tests at the preoperative interview

Exclusion criteria

  • Failed to complete two or more of assessments shown above

Trial design

447 participants in 3 patient groups

Patients categorized as having no frailty on the frailty item, assessed by four domains
Description:
cognitive, emotional, physical, and nutritional.
Patients exhibiting the early signs that may lead to frailty, assessed in four domains
Description:
cognitive, emotional, physical, and nutritional.
Patients categorized as having frailty on the frailty item, assessed by four domains
Description:
cognitive, emotional, physical, and nutritional.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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