Impact of Previous Open Renal Surgery on Percutaneous Nephrolithotomy Complications

Sohag University

Status: Completed

Conditions: Open Renal Surgery; Percutaneous Nephrolithotomy; Complications

Treatments: Procedure: Percutaneous Nephrolithotomy

Study type: Observational

Funder types: Other

Identifiers

NCT07097883

Soh-Med-25-6-1PD

Details and patient eligibility

About

This study compared percutaneous nephrolithotomy (PCNL) complications in cases with or without previous renal surgery.

Full description

Percutaneous nephrolithotomy (PCNL) is a cornerstone in managing large renal calculi. However, in patients with a history of previous open renal surgery (POS), retroperitoneal scarring, altered anatomy, and vascular complications may influence PCNL outcomes.

The literature remains inconsistent regarding whether POS negatively impacts PCNL success or increases complications. Therefore, this study aims to clarify the comparative safety and efficacy of PCNL in patients with and without prior open renal surgery.

Enrollment: 200 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients (≥18 years).
• Both sexes.
• Undergoing percutaneous nephrolithotomy (PCNL) for renal calculi >2 cm.

Exclusion criteria

• Active urinary tract infection.
• Elevated serum creatinine >2.0 mg/dL.
• Pregnancy.
• Uncontrolled coagulopathy.
• Significant cardiopulmonary comorbidities.

Trial design

200 participants in 2 patient groups

Fresh cases

Description:

Patients with no prior renal surgery.

Treatment:

Procedure: Percutaneous Nephrolithotomy

Recurrent cases

Description:

Patients with previous open renal surgery on the same side.

Treatment:

Procedure: Percutaneous Nephrolithotomy