Impact of Probiotics Supplement on the Gut Microbiota in Caesarean-born Infants

Tongji University

Status: Unknown

Conditions: Gut Microbiota

Treatments: Dietary Supplement: probiotics

Study type: Interventional

Funder types: Other

Identifiers

NCT05086458

SHSYEK-001

Details and patient eligibility

About

The purpose of this study is to evaluate the effect of probiotics on the gut microbiota of infants born by cesarean section.

Full description

This study aims to examine the impact of probiotics administration on the gut microbiota of infants born by cesarean section. Birth,14 days and 42 days data will be collected and put into analysis to provide some suggestions on the probiotics use in the clinical for the infants born by cesarean section.

Enrollment: 30 estimated patients

Sex: All

Ages: 1 hour to 42 days old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Neonates born by caesarean section

Exclusion criteria

• Gestational weeks <37 Birth weight <2500g or ≥4000g History of asphyxia anoxia at birth With congenital metabolic diseases or hereditary diseases With gastrointestinal diseases With infectious diseases

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

No intervention

No Intervention group

Description:

the patients in this arm will not receive probiotics.

Dietary Supplement

Experimental group

Description:

the patients in this arm will receive probiotics blend of Bifidobacterium longum, Lactobacillus acidophilus, Enterococcus faecalis for 2 weeks.

Treatment:

Dietary Supplement: probiotics