Impact of Procalcitonin on the Management of Children Aged 1 to 36 Month Presenting With a Fever Without a Source

S

St. Justine's Hospital

Status

Completed

Conditions

Procalcitonin
Bacteremia
Bacterial Infection
Fever Without Source

Treatments

Other: Procalcitonin dosage PCT-Q test (Brahms, Germany)

Study type

Interventional

Funder types

Other

Identifiers

NCT00692848
URG73

Details and patient eligibility

About

Serious bacterial infections are often difficult to detect in children with fever without source. Procalcitonin is a better blood marker of infection than White blood cell count and possibly than C-reactive protein. This could lead to a reduction in antibiotic prescription. Our objective is to evaluate the impact of Procalcitonin result on antibiotic prescription in children 1 to 36 month old with fever without source and our hypothesis is that it will lower the antibiotic prescription rate

Enrollment

384 patients

Sex

All

Ages

1 to 36 months old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Children 1-36 months
  • With rectal temperature >38.0 C
  • And no identified source of infection after history and physical examination

Exclusion criteria

acquired or congenital immunodeficiency

Trial design

Primary purpose

Diagnostic

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Quadruple Blind

384 participants in 2 patient groups

PCT+
Experimental group
Description:
Investigations include CBC, blood culture, urine analysis and culture and procalcitonin. In this arm procalcitonin result is revealed to the attending physician. The decision to treat with antibiotics or to hospitalize was left to him
Treatment:
Other: Procalcitonin dosage PCT-Q test (Brahms, Germany)
PCT-
No Intervention group
Description:
Investigations include CBC, blood culture, urine analysis and culture and procalcitonin. In this arm, procalcitonin is not revealed to the attending physician. The decision to treat with antibiotics or to hospitalize was left to him.

Trial contacts and locations

0

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location

Resources

© Copyright 2024 Veeva Systems